Table 1.

Relationships between clinical parameters, GNMT1, MAT1A protein expression, and MAT2A C/N ratio in 252 breast cancer patients.

		GNMT1			MAT1A			MAT2A (C/N Ratio)
Characteristics	No.	Low (N = 126)	High (N = 126)	p-Value	Low (N = 126)	High (N = 126)	p-Value	Low (N = 126)	High (N = 126)	p-Value
Age
<65	206	99 (48)	107 (52)	0.19	97 (47)	109 (53)	0.05	109 (53)	97 (47)	0.05
≥65	46	27 (59)	19 (41)		29 (63)	17 (37)		17 (37)	29 (63)
Stage
I, II	183	52 (28)	131 (72)	0.89	72 (39)	111 (61)	0.81	95 (52)	88 (48)	0.323
III, IV	69	19 (28)	50 (72)		26 (38)	43 (62)		31 (45)	38 (55)
ER
Negative	71	37 (52)	34 (48)	0.67	34 (48)	47 (52)	0.67	37 (52)	34 (48)	0.674
Positive	181	89 (49)	92 (51)		92 (51)	89 (49)		89 (49)	92 (51)
PR
Negative	98	54 (55)	44 (45)	0.2	50 (51)	48 (49)	0.8	49 (50)	49 (50)	1
Positive	154	72 (47)	82 (53)		76 (49)	78 (51)		77 (50)	77 (50)
HER2
Negative	170	82 (48)	88 (52)	0.42	84 (49)	86 (51)	0.79	89 (52)	81 (48)	0.282
Positive	82	44 (54)	38 (46)		42 (51)	40 (49)		37 (45)	45 (55)