Table 3.

Odds ratios and 95% confidence intervals for risk of mild/moderate and severe COVID-19 in cancer patients.

Variable	COVID-19 Negative	Mild/Moderate COVID-19	Risk of Mild/Moderate		Severe COVID-19	Risk of Severe COVID-19
	n (%)	n (%)	OR *	95% CI	n (%)	OR *	95% CI
Sex
Female	1105 (56)	66 (44)	1.00	Ref.	12 (29)	1.00	Ref.
Male	857 (44)	83 (56)	1.62	(1.16–2.27)	29 (71)	3.12	(1.58–6.14)
Age
≤60	799 (41)	54 (36)	1.00	Ref.	12 (29)	1.00	Ref.
>60	1163 (59)	95 (64)	1.21	(0.86–1.71)	29 (71)	1.66	(0.84–3.27)
SES
Low	1691 (86)	124 (83)	1.00	Ref.	33 (80)	1.00	Ref.
Middle/High	167 (9)	16 (11)	1.64	(0.93–2.88)	3 (7)	1.38	(0.40–4.76)
Ethnicity
White	1021 (52)	73 (49)	1.00	Ref.	25 (61)	1.00	Ref.
Black	227 (12)	35 (23)	2.16	(1.41–3.31)	7 (17)	1.26	(0.54–2.95)
Asian	55 (3)	3 (2)	0.76	(0.23–2.50)	4 (10)	2.97	(1.00–8.83)
Other	62 (3)	4 (3)	0.90	(0.32–2.55)	2 (5)	1.32	(0.31–5.69)
Smoking History
Never	497 (25)	53 (36)	1.00	Ref.	13 (32)	1.00	Ref.
Ever	571 (29)	51 (34)	0.91	(0.58–1.42)	16 (39)	0.90	(0.38–2.10)
Cancer Type
Solid	1778 (91)	126 (85)	1.00	Ref.	31 (76)	1.00	Ref.
Haematological	162 (8)	23 (15)	2.30	(1.38–3.83)	10 (24)	2.43	(1.00–5.90)
Tumour Stage
I-III	1103 (56)	37 (25)	1.00	Ref.	6 (15)	1.00	Ref.
IV	302 (15)	15 (10)	1.48	(0.80–2.73)	2 (5)	1.22	(0.24–6.06)
Treatment Paradigm
No active treatment	78 (4)	15 (10)	1.00	Ref.	3 (7)	1.00	Ref.
Radical/Curative	853 (43)	58 (39)	0.37	(0.20–0.69)	13 (32)	0.37	(0.10–1.38)
Palliative	892 (45)	59 (40)	0.36	(0.19–0.66)	19 (46)	0.56	(0.16–1.95)
Time since cancer diagnosis
<1 year	878 (45)	83 (56)	1.00	Ref.	13 (32)	1.00	Ref.
1–2 years	317 (16)	18 (12)	0.63	(0.36–1.11)	5 (12)	1.27	(0.41–3.90)
2–5 years	370 (19)	20 (13)	0.59	(0.34–1.02)	9 (22)	1.69	(0.62–4.59)
≥5 years	287 (15)	24 (16)	0.87	(0.51–1.46)	12 (29)	2.89	(1.12–7.50)

* Adjusted models according to DAG in the Appendix A.