Table 2.

Patient demographics and disease characteristics. Chemotherapy regimens were given in an advanced setting, unless stated otherwise.

Pt #	Gender	Age	WHO-PS	Primary Diagnosis	Earlier Surgery	Earlier Systemic Therapy	Earlier Radiotherapy	Time Since Initial Diagnosis
								(in Years)
1	Male	54	0	Chondrosarcoma	Resection of tumor of the right knee	None	No	5.6
2	Male	49	1	Cholangiocarcinoma	Right hemihepatectomy	Gemcitabine/cisplatin	No (during study)	3.92
3	Male	51	2	Chondrosarcoma	Resection of left pelvic tumor	Sirolimus/cyclophosphamide	Yes	3.25
4	Male	64	0	Cholangiocarcinoma	Exploratory laparotomy	Gemcitabine/cisplatin	No	3.3
5	Male	58	1	Cholangiocarcinoma	Right hemihepatectomy	Gemcitabine/cisplatin	No	3.72
6	Male	57	1	Cholangiocarcinoma	None	Gemcitabine/cisplatin	No	2.84
7	Male	82	2	Cholangiocarcinoma	None	Gemcitabine/cisplatin, pembrolizumab	Yes	3.75
8	Female	53	1	Cholangiocarcinoma	None	Gemcitabine/cisplatin	No	2.33
9	Male	70	0	Cholangiocarcinoma	Right hemihepatectomy	Gemcitabine/cisplatin, capecitabine/oxaliplatin	No	2.58
10	Male	39	0	Cholangiocarcinoma	Right hemihepatectomy	Gemcitabine/cisplatin, folfirinox	No	3.82
11	Male	50	0	Cholangiocarcinoma	None	Gemcitabine/cisplatin, gemcitabine/oxaliplatin	No	3.25
12	Male	39	0	Chondrosarcoma	Resection of right scapular tumor	Sirolimus/cyclophosphamide	No	2.96
13	Female	42	0	Cholangiocarcinoma	None	Gemcitabine/cisplatin	Yes	1.53
14	Male	46	1	Glioma	Tumor resection	Temozolomide	Yes	6.43
15	Male	34	1	Glioma	Tumor resection right frontal	Temozolomide, lomustine	Yes	5.33
16	Female	63	0	Cholangiocarcinoma	Right hemihepatectomy	Gemcitabine/cisplatin	No	2.50
17	Male	64	0	Cholangiocarcinoma	None	Gemcitabine/cisplatin, CAPOX	No	1.50

Abbreviations: Pt #, patient number; WHO-PS, World Health Organization- Performance Status; CAPOX, Capecitabine/Oxaliplatin.