Table 1. Relative Energies, Boltzmann Factor, and Equilibrium Mole Fraction of All Structurally Distinct Conformations of Folate.

conformation no.	relative energy (kcal)	Boltzmann factor	equilibrium mole fraction
1	0.36	0.55	0.17
2	2.94	0.01	0.00
3	2.34	0.02	0.01
4	2.93	0.01	0.00
5	3.42	0.00	0.00
6	1.65	0.06	0.02
7	2.52	0.01	0.00
8	2.71	0.01	0.00
9	3.09	0.01	0.00
10	6.83	0.00	0.00
11	0.39	0.51	0.16
12	2.91	0.01	0.00
13	1.20	0.13	0.04
14	4.17	0.00	0.00
15	0.46	0.46	0.15
16	2.19	0.02	0.01
17	7.47	0.00	0.00
18	3.82	0.00	0.00
19	1.20	0.13	0.04
20	1.77	0.05	0.02
21	4.44	0.00	0.00
22	6.18	0.00	0.00
23	2.68	0.01	0.00
24	0.00	1.00	0.32
25	3.58	0.00	0.00
26	1.18	0.14	0.04