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PK parameters (mean ± sd) of Gemtuzumab Ozogamicin in children following 9 mg/m2 in period 1 as a function of age.
| Age (Years) | CL (L/h) | Vss (L) | Half-Life (h) |
|---|---|---|---|
| Infants (0–2), n = 2 | 0.03 ± NA | 2.9 ± NA | 113 ± NA |
| Children (3–11), n = 5 | 0.06 ± 0.03 | 3.9 ± 1.9 | 45.6 ± 30.8 |
| Adolescents (12–16), n = 7 | 0.26 ± 0.30 | 9.4 ± 6.6 | 62.0 ± 16.5 |
| Adults (n = 59) | 0.27 ± 0.23 | 20.9 ± 21.5 | 72.4 ± 42.0 |
NA because n = 2.
