Figure 1.

Liposomal SNA (L-SNA) design parameters. (a) Schematic representation of the L-SNA, wherein DNA (green) is embedded into the outer phospholipid membrane of a liposome core using a hydrophobic DNA anchor (depicted in red). The modularity of the L-SNA architecture allows for the rapid generation of diverse constructs by using different phospholipids. (b) Chemical structure and phase transition temperature (T_C) of the phospholipids used in the synthesis of the L-SNAs employed in these studies.