Fig. 5. (A) DC maturation (CD11c⁺CD80⁺CD86⁺) when treated with LPS or supernatant of 4T1 cells incubated with PBS, cisplatin, or Ir-cR8. (B) Treatment schedule: 4T1 cells were implanted into left and right flank on day 0 and day 4, respectively, and PBS or Ir-cR8 (0.1 μmol) was injected into the tumour of the left flank on day 7. The tumours of the right flank were collected on day 14 for cytokine assay. (C) Cytokine level in right flank tumour from mice (n = 3) at day 14, *P < 0.05.