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. 2021 May 27;21:235. doi: 10.1186/s12886-021-01994-4

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Differential expression of genes in satellite cells of extraocular muscles in the complete lateral rectus paralysis group. A. Volcano plot of the differentially expressed genes. The x axis is log2 (fold change) while the y axis is -log10 (P-value). Black dots indicate non-differentially expressed genes while the red dots indicate increases in expressed genes and green dots indicate decreases in expressed genes. B. Significance Analysis of Microarrays (SAM) of Affymetrix GeneChip® Human Genome U133 Plus 2.0 Array (HG-U133 Plus 2.0) from age and sex matched extraocular muscles of group A (Paralytic esotropia) and group B (Concomitant esotropia). C. The upper 30 significant enriched GO terms. The abscissa is −log10 (p − Value) and the ordinate is the significant enriched GO terms. Red indicates molecular function terms, blue indicates biological process terms and green indicates cellular component terms