Table 2.

Depth of Transfer RNA–Derived Fragment Discovery Across 3 Platforms Over 345 Samples

Tool	Alignment Strategy	Total Read Counts of tRFs	Total Read Counts of tRFs After Filter	Proportion of tRF Reads After Filter	Total tRF Counts	Total tRF Counts After Filter
tRFcluster	1 mismatch	176 584 695	175 683 293	0.99	540	324
MINTmap	0 mismatch	143 792 494	133 141 746	0.93	79 404	858
tDRmapper	2 mismatches and 3 deletions	193 952 012	187 599 715	0.97	1469	374

Abbreviation: tRF, transfer RNA–derived fragment.