Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 20;36(4):316–325. doi: 10.1089/cbr.2020.4492

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Jyoti Roy et al. 2021; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License [CC-BY-NC] (http://creativecommons.org/licenses/by-nc/4.0/) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are cited.

PMC Copyright notice

FIG. 4. — Competition binding assay and immunoreactivity plots. Representative plots from an in vitro [⁸⁹Zr]Zr-3,2-HOPO-MSLN-mAb (A) and [⁸⁹Zr]Zr-DFO-MSLN-mAb, (B) competition-binding assays using unlabeled MSLN targeted monoclonal antibody (self-displacement, Morris method) with HT29-MSLN cells. Each point (average of duplicates) represents cell-bound CPM. Representative plots for determination of the % immunoreactivity (immunoreactive fraction) of ⁸⁹Zr]Zr-3,2-HOPO-MSLN-mAb (C) and [⁸⁹Zr]Zr-DFO-MSLN-mAb (D) from the same batch by the Morris method: representative plot (linear regression curve fit), immunoreactivity for ⁸⁹Zr]Zr-3,2-HOPO-MSLN-mAb = 96% and [⁸⁹Zr]Zr-DFO-MSLN-mAb = 95%. CPM, count per minute.