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. 2021 May 28;22(9):572–587. doi: 10.1038/s41576-021-00367-3

Table 1.

An overview of long-read-based population studies

Study Organism and category Technologya and analysis approach Sample sizeb Genome size (Mbp) Ref.
Kou et al. (2020)

Rice

Agriculture

PacBio

Assembly comparison and read mapping

15 (LR); 393 (SR) 430 129
Weissensteiner et al. (2020)

Crow

Evolution

PacBio

Read mapping

33 (LR); 127 (SR) 1,300 35
Chakraborty et al. (2019)

Drosophila

Evolution

PacBio

Assembly comparison

14 (LR) 180 34
Jiao & Schneeberger (2020)

Arabidopsis

Evolution

PacBio

Assembly comparison

7 (LR) 135 130
Alonge et al. (2020)

Tomato

Agriculture

ONT

Read mapping

100 (LR) 950 32
Beyter et al. (2020)

Human

Human evolution

ONT

Read mapping

3622 (LR) 3,200 11
Tusso et al. (2019)

Yeast

Evolution

ONT and PacBio

Assembly comparison and read mapping

17 (LR); 161 (SR) 12 30
Liu et al. (2020)

Soy bean

Agriculture

PacBio

Assembly comparison

26 (LR) 1,150 33
Chawla et al. (2020)

Rapeseed

Agriculture

ONT and PacBio

Read mapping

12 (LR) 1,132 131
Hiatt et al. (2020)

Human

Human evolution

PacBio

Assembly comparison and read mapping

18 (LR) 3,200 18
Mitsuhashi et al. (2020)

Human

Human evolution

ONT and PacBio

Read mapping

37 (LR) 3,200 132
Shafin et al. (2020)

Human

Human evolution

ONT

Assembly comparison

11 (LR) 3,200 25
De Roeck et al. (2020)

Human

Human evolution

ONT

Read mapping

11 (LR) 3,200 133
Chaisson et al. (2019)

Human

Human evolution

ONT and PacBio

Assembly comparison

9 (LR) 3,200 10
Morena-Barrio et al. (2020)

Human

Human evolution

ONT

Read mapping

19 (LR) 3,200 19
Song et al. (2020)

Rapeseed

Agriculture

PacBio

Assembly comparison

8 (LR) 1,132 134
Sone et al. (2019)

Human

Human evolution

ONT and PacBio

Read mapping

17 (LR) 3,200 20
Kim et al. (2020)

Drosophila

Evolution

ONT

Assembly comparison

101 (LR) 180 135
Pauper et al. (2020)

Human

Human evolution

PacBio

Read mapping

15 (LR) 3,200 136
Ebert et al. (2020)

Human

Human evolution

PacBio

Assembly comparison

64 (LR) 3,200 46
Quan et al. (2020)

Human

Human evolution

ONT

Read mapping

25 (LR) 3,200 137
Hufford et al. (2021)

Maize

Agriculture

PacBio

Assembly comparison

26 (LR) 2,200 13
Hu et al. (2021)

Maize

Agriculture

PacBio

Assembly comparison

6 (LR) 2,200 138
Wu et al. (2021)

Human

Human evolution

ONT and PacBio

Read mapping

405 (LR) 3,200 12

aTwo main platforms are used in long-read sequencing projects, Pacific Biosciences (PacBio) high fidelity (HiFi) and Oxford Nanopore Technologies (ONT) PromethION. bSample sizes for long-read (LR) and short-read (SR) sequencing are specified.