Table 4.
Chemotherapy response according to APOBEC3B expression.
| Total | APOBEC3B * Low | APOBEC3B ** High | p-Value | |
|---|---|---|---|---|
| CR or PR | 59 | 12 | 24 | 0.227 |
| SD or PD | 35 | 11 | 47 | |
| CR, PR or SD | 73 | 15 | 58 | 0.099 |
| PD | 21 | 8 | 13 | |
| Total | APOBEC3B low | APOBEC3B high | ||
| CR | 18 | 2 | 16 | |
| PR | 41 | 10 | 31 | |
| SD | 14 | 3 | 11 | |
| PD | 21 | 8 | 13 | |
| Total | 94 | 23 | 71 |
* Low: H-score ≤ 90, ** High, H-score > 90, H-score (nucleus + cytoplasm) = intensity × proportion. CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease, these terms of response evaluation follow the definition of RECIST criteria v1.1.