Table 3.
Characteristics of 22 patients with or without fibrosis at histological examination.
| Fibrosis (10) | No fibrosis (12) | p value | |
|---|---|---|---|
| General characteristics | |||
| Age, years | 66 [64.5–73.7] | 65 [58–71] | 0.44 |
| Male sex | 70% | 73% | 0.99 |
| SAPS II, points | 51 [43.7–61.7] | 62 [54.7–69.5] | 0.23 |
| Duration of mechanical ventilation, days | 26 [20–29] | 8 [5.75–11.75] | <0.01 |
| Steroid therapy | 70% | 33% | 0.19 |
| Delay between the onset of ventilation and start of steroids, days | 10 [4–15] | 5 [2–9] | 0.51 |
| Ventilatory parameters collected at time of death | |||
| FiO2 | 0.97 [0.42–1] | 1 [0.5–1] | 0.68 |
| PEEP, mean cmH2O | 5.6 [5–7.5] | 9 [5–10.5] | 0.21 |
| PaO2/FiO2 | 200 [72–219] | 114 [76–191.5] | 0.41 |
| Dynamic compliance, ml/cmH2O | 19 [14–23.5] | 23 [18–24.7] | 0.56 |
Data are n (%) or mean (SD) unless otherwise stated. SAPS 2, simplified acute physiological score; PEEP, positive end-expiratory pressure.