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. 2021 May 28;29:100930. doi: 10.1016/j.mgene.2021.100930

Fig. 3.

Fig. 3

Molecular dynamics and simulation analysis of WT and V160M mutant TMPRSS2. Cartoon representation showing the N-terminal domain TMPRSS2 (A) Wild-Type TMPRSS2, (B) V160M mutant TMPRSS2 and (C and D) Superimposing of Wild-Type and V160M structures. The position of amino-acid Valine and Methionine are shown in pink sticks and change in the TMPRSS2 secondary structure is noticeable. (E and F) B-factor profiles of wild type and V160M mutant structure of TMPRSS2. The difference in the domain oscillation or B-factor resulting in structural change are marked in red dashed box.