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. 2021 May 25;13:1759720X211016661. doi: 10.1177/1759720X211016661

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© The Author(s), 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Hyperuricemia and multivariable-adjusted and unadjusted risk of chronic kidney disease, end stage kidney disease, albuminuria and estimated glomerular filtration rate decline in longitudinal analysis. (a) OR of rapid eGFR decline (⩾3 ml/min/per 1.73 m²/year) for highest versus lowest serum uric acid quintile. (b) Combined HR/OR of albuminuria for highest serum uric acid tertile versus lowest tertile. (c) Combined OR/HR of CKD for comparison of highest serum uric acid quartile versus lowest quartile. (d) HR of kidney failure for highest serum uric acid tertile versus lowest tertile. (e) Combined HR/OR of CKD for hyperuricemia versus normouricemia. (f) Combined HR/OR of rapid eGFR decline (⩾3 ml/min/per 1.73 m²/year) for every 1 mg/dl increase in serum urate.

CI, confidence interval; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; HR, hazard ratio; IV, inverse variance; OR, odds ratio; sUA, serum urate