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. 2021 May 28;14:41. doi: 10.1186/s13047-021-00480-w

Table 2.

Summary of the included studies

Authors Country Study type Mode of data collection Study population Defining CAI Exclusion criteria Prevalence of CAI, n(%) Prevalence of CAI within participants with history of ankle sprains, n(%) Participants with history of ankle sprain, n(%)
Schmitt et al. [18] France Descriptive longitudinal study Questionnaires French soldiers aged 32.2 (N = 1238) with a history of ankle sprain (n = 65) Based on IAC using IdFAI IAC 28 (2) 28/65 (43) 65 (5)
Donovan et al. [19] USA Cross-sectional study Questionnaires

Athletes 8 from sports clubs and high Athletes in high schools in Wisconsin (N = 1002)

 Female (n = 505): 15.7 ± 1.7 years

 Male (n = 497): 15.6 ± 1.9 years

A history of ankle sprain and perceived ankle instability (evaluated using IdFAI) Without history of injury 200 (20) 200/262 (76) 262 (26)
Koshino et al. [20] Japan Cross-sectional study Questionnaires

Japanese Collegiate athletes with LAS (N = 470)

CAI (n = 47): 20.0 ± 1.2 years, 1.70 ± 0.7 m, 65.5 ± 11.5 kg

Coper (n = 20): 20.5 ± 1.4 years, 1.68 ± 0.06 m, 63.8 ± 10.3 kg

Based on IAC using CAIT

Research criteria: IAC

Clinical criteria: IAC without exclusion criteria

47 (10)

93 (20)

47/212 (22)

93/212 (44)

212 (45)
Holland et al. [21] USA Cross-sectional study Questionnaires

Students in western North Carolina(N = 201)

 Uninjured (n = 86): 16.0 years, 1.69 m, 62.0 kg

 Coper (n = 16): 15.38 years, 1.66 m, 65.2 kg

 Potentially unstable (n = 40): 15.6 years, 1.65 m, 60.9 kg

 Unstable (n = 59): 15.68 years, 1.68 m, 62.5 kg

Based on IAC using IdFAI Missing data 59 (29) 59/115 (51) 115 (57)
Doherty et al. [22] Ireland Cohort study Questionnaires

Physical active individuals with LAS (N = 70)

 CAI (n = 28): 23.2 years, 75.5 kg, 1.72 m

 LAS coper (n = 42): 22.7 years, 73.4 kg, 1.73 m

Based on IAC using CAIT IAC NA 28/70 (40) NA
Attenborough et al. [23] Australia Cross-sectional study Questionnaires Ankle joint laxity

Female netball players in Sydney(N = 96)

 Club (n = 42): 24.1 ± 7.9 years, 1.67 ± 0.05 m, 68.5 ± 15.9 kg

 Inter-district (n = 54): 19.4 ± 3.5 years, 1.73 ± 0.06 m, 72.0 ± 12.7 kg

Previous ankle sprain +

Recurrent ankle sprain, perceived ankle instability (CAIT), mechanical ankle instability

A lower limb injury in the 6 months prior to testing a history of ankle surgery or ankle fracture all previous ankle sprains occurred a minimum of 6 months prior 44 (46) 44/69 (64) 69 (72)
Simon et al. [24] USA Exploratory study Questionnaires

Dancer (N = 77)

19.61 ± 2.53 years, dance experience: 13.61 ± 3.16 years

perceived ankle instability (IdFAI) A history of fracture or surgery in the lower extremities. 41 (53) 41/54 (76) 54 (70)
Tanen et al. [25] USA Descriptive epidemiological survey Questionnaires

Athletes (N = 512)

Collegiate athletes (n = 316) 19.6 ± 1.2 years

high school athletes (n = 196) 15.9 ± 1.2 years

Perceived ankle instability (CAIT and AII) A history of an ankle fracture, ankle surgery, neurological disorder such as, Parkinson’s disease, amyotrophic lateral sclerosis, or multiple sclerosis, or failed to completely answer the questionnaires. 120 (23) 120/391 (31) 391 (76)
Kobayashi et al. [26] Japan Cross-sectional study Questionnaires

Female athletes (N = 138)

Aged 18–23

21.8 ± 0.4 years, 1.66 m, 57.0 kg

Based on IAC using CAIT IAC 10 (7) 10/106 (9) 106 (77)

IAC The International Ankle Consortium, CAIT The Cumberland Ankle Instability Tool, AII The ankle Instability Instrument, IdFAI The Identification of functional Ankle Instability, NA not applicable