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. 2021 May 27;21:281. doi: 10.1186/s12935-021-01968-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Identification and validation of the hnRNPA2B1 target mRNAs in GC cells. a GO enrichment analysis of hnRNPA2B1 positively co-expressed genes (Pearson > 0.6, padj < 0.05) in cBioPortal TCGA dataset. b GO enrichment analysis of hnRNPA2B1 negatively co-expressed genes (Pearson < -0.6, padj < 0.05) in cBioPortal TCGA dataset. c The hnRNPA2B1 binding sites on BIRC5 mRNA by analyzing ENCORI database. d Schematic representation of the exons encoding three protein coding isoforms of BIRC5 in Ensembl. Arrows indicated the sites for qRT-PCR primers. e RIP-PCR analysis for the interaction of hnRNPA2B1 protein and BIRC5 mRNA. Data are presented as means ± S.D