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. 2021 May 27;9:39. doi: 10.1186/s40364-021-00295-8

Fig. 1.

Fig. 1

The mechanism of action of m6A modification in breast cancer. m6A modification consists of three vital components: writers, also termed methyltransferases; erasers, or demethylases, which remove the m6A modification; and readers, which recognize m6A-modified sites and further regulate m6A modification. m6A modifications affect RNA transcription, RNA processing, RNA splicing, RNA degradation, RNA export and RNA translation