Table 2.
Performance of prediction model among study samples
| Study samples | Number of patients | Number of events | Events rate (95% CI), % | Predicted events number | Discrimination | Calibration | ||
| AUC (95% CI) | Predictive ability* (median rate of lowest to highest decile) | Slope (95% CI) | Intercept (95% CI) | |||||
| Development | 8010 | 935 | 11.67 (10.98 to 12.40) | 935 | 0.848 (0.834 to 0.864) | 0.75% to 47.57% | 0.98 (0.96 to 0.99) | 0.003 (0.001 to 0.005) |
| External validation #1 | 4485 | 395 | 8.81 (7.99 to 9.67) | 283.1 | 0.738 (0.703 to 0.768) | 0.75% to 25.58% | 0.84 (0.70 to 0.98) | 0.035 (0.024 to 0.045) |
| External validation #2 | 11 223 | 1285 | 11.45 (10.87 to 12.05) | 1087.3 | 0.798 (0.783 to 0.814) | 0.75% to 40.1% | 0.97 (0.90 to 1.04) | 0.020 (0.014 to 0.027) |
*Observed rates in deciles determined by estimated model.
AUC, area under ROC curve.