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| Factor | Level | Hazard ratio (95% CI) | p-value | |
|---|---|---|---|---|
| NLR at baseline | <5 | ≤6 months | Ref | 0.0001 |
| ≥5 | 3.37 (1.81, 6.26) | |||
| NLR at baseline | <5 | >6 months | Ref | 0.7681 |
| ≥5 | 0.86 (0.32, 2.30) | |||
| BMI | ≥25 | Ref | 0.1491 | |
| <25 | 1.43 (0.88, 2.32) | |||
| Smoking history | Never | Ref | 0.1694 | |
| Current/prior smokers (1–20 pack-years) | 1.75 (0.71, 4.33) | |||
| Current/prior smokers (>20 pack-years) | 1.00 (0.45, 2.22) |
NLR: Neutrophil-to-lymphocyte ratio.
