Table 2:

Summary of the most commonly mentioned MCTAs in this review.

MCTA	Primary Motivation for Use	Location of Users in Publications	Data Availability/Privacy	Additional Information of note for research
Clue	T rack cycles [16, 26]	United States [16]	Authors were employed at company that produced Clue, so they had access to data. [26]	Is gender inclusive [16, 38] Has a lot of features for tracking behavior [43, 16, 26] Most users do not log pregnancy test or other biomarker-test predictive of pregnancy [26]
CycleBeads	Prevent pregnancy [29] Observe Cycle [30]	Egypt, Ghana, India, Jordan, Kenya, Nigeria, and Rwanda [29] Kenya [30]	Signing up for the app allows for de-identified user data to be utilized for research for these specific researchers [29] Required in-app recruitment for research [30]
DOT	Prevent pregnancy [51]	United States [51]	Requires in-app recruitment for research [51] A written consent for was required after enrollment [34]	Effective for women with longer and shorter than average cycle lengths [45]
Kindara	Promote pregnancy [13]	Mostly United States [13]	N/A
LunaLuna	Plan pregnancy [22]	Japan [22]	Authors were employed at company that produced LunaLuna, so they had access to data. [22]
Natural Cycles	Prevent pregnancy [5–9, 23, 48]	Sweden and Switzerland [7]; UK, United States and Sweden[6, 23]; Sweden [5,8,9]	Signing up for the app allows for de-identified user data to be utilized for research [8]	Certified in Europe [46] and the United States [28] as a form of contraception
Ovia	Plan pregnancy [20,25]	United States [20,25]	Signing up for the app allows for de-identified user data to be utilized for research [20,25]	More representative of a subfertile population [20]
Sympto	Prevent pregnancy [13]	Mostly Europe [13]	N/A