Fig. 4.

A–C: Relative hippocampal mRNA expression of various Fabps in Rev-erbα KO vs. WT mice under normal (LD) conditions. Levels of Fabp3 (A) or Fabp5. (B) are unaffected by Rev-erbα deficiency, however, Fabp7 shows a significant increase in expression based on genotype. ∗p ​< ​0.001, N ​= ​4–7 per group, Student’s t-test. ZT ​= ​zeitgeber time. Hippocampal mRNA expression normalized to genotype to visualize the circadian rhythmicity of Fabp3 (D), Fabp5 (E), and Fabp7 (F). Fabp7 circadian rhythmicity was significantly disrupted in Rev-erba KO mice (adj. p ​= ​0.184; JTK_Cycle) compared to WT mice (adj. p ​< ​0.001; JTK_Cycle).