Table 2.

Analysis of Gene Ontology in Rev-erbα ChIP-seq genes. Highest fold enriched Gene Ontology classes for Biological Process, Molecular Function and Cellular Component are listed with most highly enriched on top.

PANTHER GO-Slim Biological Process	Number of Genes	Fold Enrichment	Raw P-value	FDR
circadian regulation of gene expression	11	10.65	0.000000207	0.00000705
neg. reg. of transforming growth factor beta receptor signaling pathway	4	10.33	0.0021	0.0312
regulation of circadian rhythm	4	8.85	0.00314	0.0448
chondroitin sulfate proteoglycan biosynthetic process	5	6.46	0.00272	0.0393
protein demethylation	5	6.46	0.00272	0.0391
protein autophosphorylation	10	3.87	0.000719	0.0118
regulation of actin filament organization	15	2.8	0.000803	0.013
response to abiotic stimulus	16	2.75	0.000638	0.0106
positive regulation of transcription by RNA polymerase II	38	2.52	0.00000206	0.0000599
regulation of cellular component size	17	2.42	0.00196	0.0295
positive reg. of nucleobase-containing compound metabolic process	54	2.34	9.73E-08	0.00000342
PANTHER GO-Slim Molecular Function
demethylase activity	9	5.17	0.000228	0.00452
flavin adenine dinucleotide binding	10	4.56	0.000242	0.00463
transcription coregulator activity	40	3.04	8.74E-09	0.000000606
phosphoprotein phosphatase activity	19	2.21	0.00295	0.0409
small molecule binding	44	1.76	0.000706	0.0112
protein kinase activity	51	1.62	0.00177	0.0266
PANTHER GO-Slim Cellular Component
vacuolar membrane	13	2.76	0.00196	0.0344
Golgi membrane	14	2.55	0.00255	0.0418
transcription regulator complex	31	2.54	0.0000114	0.000386
neuron projection	42	1.72	0.00181	0.0328
transferase complex	50	1.69	0.000921	0.0187
bounding membrane of organelle	43	1.66	0.00248	0.0421
nucleoplasm	54	1.65	0.000836	0.0185
chromatin	67	1.56	0.000896	0.019