Table 1.
CTCs can be used to distinguish lung cancer patients from the control (HD + BLD patients).
| Group | n | Average (Median) Age (years) | CTCs ≥ 1 (per 7.5 mL) | CTC Detection Rate (%) | Average CTC Count (Range) | P |
|---|---|---|---|---|---|---|
| HD | 9 | 58.78 (61) | 0 | 0 | 0 | <0.0001 |
| BLD | 21 | 51.57 (55) | 10 | 47.62 | 0.5 (0-3) | |
| LC | 78 | 58.55 (60) | 65 | 83.33 | 2.47 (0-8) | |
| HD | 9 | 58.78 (61) | 0 | 0 | 0 | <0.0001 |
| BLD | 21 | 51.57 (55) | 10 | 47.62 | 0.5 (0-3) | |
| TNM I | 30 | 55.17 (55.5) | 22 | 73.33 | 1.6 (0-4) | |
| TNM II | 7 | 60.29 (60) | 6 | 85.71 | 2 (0-4) | |
| TNM III | 13 | 61.38 (63) | 11 | 84.62 | 2.54 (0-5) | |
| TNM IV | 28 | 60.43 (61.5) | 26 | 92.86 | 3.5 (0-8) |
CTCs, circulating tumor cells; HD, healthy donor; BLD, benign lung disease; n, number; LC, lung cancer; TNM, tumor-node-metastasis.
Bold values mean statistically significant. Bold values are all less than 0.05.