Table 1.
Baseline patient characteristics stratified by inflammatory marker levels in grade IV glioma.
| Variables | Complete dataset | 1:1 matched dataset | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Total (n=62) | % | SIRI ≤1.26 (n=29, 46.8%) | SIRI >1.26 (n=33, 53.2%) | p | Total (n=48) | % | SIRI ≤1.26 (n=24, 50.0%) | SIRI >1.26 (n=24, 50.0%) | p | |
| N/ M ± SD | N/ M ± SD | N/ M ± SD | N/ M ± SD | N/ M ± SD | N/ M ± SD | |||||
| Age | 50.44 ± 14.642 | 50.41 ± 16.961 | 50.45 ± 12.528 | 0.991 | 52.04 ± 14.244 | 51.39 ± 16.303 | 52.70 ± 12.178 | 0.760 | ||
| Sex | ||||||||||
| female | 32 | 51.6% | 14 | 18 | 0.622 | 24 | 52.2% | 12 | 12 | 1.000 |
| male | 30 | 48.4% | 15 | 15 | 22 | 47.8% | 11 | 11 | ||
| Main location | ||||||||||
| frontal | 37 | 59.7% | 16 | 21 | 0.498 | 27 | 58.7% | 13 | 14 | 0.765 |
| parietal | 20 | 32.3% | 10 | 10 | 0.725 | 16 | 34.8% | 9 | 7 | 0.536 |
| occipital | 11 | 17.7% | 6 | 5 | 0.569 | 8 | 17.4% | 4 | 4 | 1.000 |
| temporal | 13 | 21.0% | 7 | 6 | 0.565 | 8 | 17.4% | 5 | 3 | 0.699 |
| insular | 2 | 3.2% | 0 | 2 | 0.494 | 2 | 4.3% | 0 | 2 | 0.489 |
| other | 9 | 14.5% | 4 | 5 | 1.000 | 7 | 15.2% | 4 | 3 | 1.000 |
| No. of glioma | ||||||||||
| single | 55 | 88.7% | 25 | 30 | 0.696 | 41 | 89.1% | 21 | 20 | 1.000 |
| multiple | 7 | 11.3% | 4 | 3 | 5 | 10.9% | 2 | 3 | ||
| Extent of resection | ||||||||||
| PR | 1 | 1.6% | 0 | 1 | 0.112 | 1 | 2.2% | 0 | 1 | 0.177 |
| STR | 7 | 11.3% | 4 | 3 | 6 | 13.0% | 4 | 2 | ||
| NTR | 8 | 12.9% | 1 | 7 | 6 | 13.0% | 1 | 5 | ||
| GTR | 46 | 74.2% | 24 | 22 | 33 | 71.7% | 18 | 15 | ||
| IDH mutation | ||||||||||
| no | 42 | 67.7% | 23 | 19 | 0.068 | 35 | 76.1% | 17 | 18 | 0.730 |
| yes | 20 | 32.3% | 6 | 14 | 11 | 23.9% | 6 | 5 | ||
| MGMT methylation | ||||||||||
| no | 41 | 66.1% | 22 | 19 | 0.129 | 32 | 69.6% | 16 | 16 | 1.000 |
| yes | 21 | 33.9% | 7 | 14 | 14 | 30.4% | 7 | 7 | ||
| 1p19q deletion | ||||||||||
| no | 62 | 100% | 29 | 33 | NA | 46 | 100% | 23 | 23 | NA |
| yes | 0 | 0% | 0 | 0 | 0 | 0.0% | 0 | 0 | ||
| ATRX mutation | ||||||||||
| no | 56 | 90.3% | 24 | 32 | 0.089 | 42 | 91.3% | 20 | 22 | 0.608 |
| yes | 6 | 9.7% | 5 | 1 | 4 | 8.7% | 3 | 1 | ||
| TP53 | ||||||||||
| negative | 20 | 32.3% | 12 | 8 | 0.150 | 15 | 32.6% | 10 | 5 | 0.116 |
| positive | 42 | 67.7% | 17 | 25 | 31 | 67.4% | 13 | 18 | ||
| Ki-67 | 28.11 ± 14.724 | 29.11 ± 13.747 | 27.27 ± 15.667 | 0.632 | 28.04 ± 14.317 | 27.61 ± 14.051 | 28.48 ± 14.881 | 0.839 | ||
| Epilepsy before surgery | ||||||||||
| no | 51 | 82.3% | 24 | 27 | 0.923 | 37 | 80.4% | 20 | 17 | 0.459 |
| yes | 11 | 17.7% | 5 | 6 | 9 | 19.6% | 3 | 6 | ||
GTR, gross total resection; M, mean; N, number; NA, not applicable; No., number; NTR, near total resection; PR, partial resection; SD, standard deviation; SIRI, systemic inflammatory response index; STR, subtotal resection.