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. 2021 May 14;11:548243. doi: 10.3389/fonc.2021.548243

Figure 2.

Figure 2

MRM analysis of Meningioma CSF and tissue samples. (A) Radiological images of Meningioma – contrast MRI images (axial, sagittal and coronal views, respectively); (B) Representative peak shape for AATVGSLAGQPLQER and bar plots of AATVGSLAGQPLQER, LGPLVEQGR and SELEEQLTPVAEETR, respectively showing overexpression of APOE in Grade II meningioma (n=4) as compared to Grade I meningioma (n=3) in CSF samples; (C) Representative peak shape for AQGFTEDTIVFLPQTDK and bar plots of AQGFTEDTIVFLPQTDK, TMLLQPAGSLGSYSYR and WFSAGLASNSSWLR, respectively showing overexpression of PTGDS in Grade II meningioma as compared to Grade I meningioma in CSF samples; (D) Representative MRM peak for one peptide of CLU and bar plots depicting the increased expression of peptides EILSVDCSTNNPSQAK, ELDESLQVAER and LFDSDPITVTVPVEVSR of CLU in Meningioma tumor tissue samples (n=6) as compared to arachnoid controls (n=3).