FIGURE 7.

Dose‐dependent effect of BMS‐724296 (top panel), apixaban (middle panel), and dabigatran (bottom panel) on thrombus reduction and BT in NHPs. Thrombus reduction was expressed as a percentage reduction of drug‐treated thrombus weight relative to thrombus weight in the control artery. BT effect was expressed as a ratio of drug‐treated value versus the mean vehicle‐treated value. Data are mean ± SEM. Group sizes were reported in the Figure 2 legend. BT, bleeding time; i.v., intravenous; NHP, nonhuman primate; SEM, standard error of the mean