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. 2020 Sep 25;11(41):11189–11194. doi: 10.1039/d0sc04032k

Evaluation of N,P-iridium catalysts in the asymmetric hydrogenation of 1aa.

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a

Reaction conditions: 0.05 mmol of 1a, 1 mol% catalyst, 0.5 mL CH2Cl2, 10 bar H2. Conversion was determined by 1H-NMR spectroscopy. Enantiomeric excess was determined by SFC.