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| Entry | Solvent | H2 (bar) | Catalyst (mol%) | Conversion (%) | de-F (%) | ee (%) |
| 1 | CH2Cl2 | 10 | 1.0 | 99 | <1 | 97 |
| 2 | DCE | 10 | 1.0 | 99 | 3 | 97 |
| 3 | PhCF3 | 10 | 1.0 | 98 | 3 | 97 |
| 4 | CH2Cl2 | 4 | 1.0 | 99 | 2 | 97 |
| 5 | CH2Cl2 | 10 | 0.5 | 99 | 4 | 97 |
Reaction conditions: 0.05 mmol of 1a, 0.5 mL solvent. Conversion was determined by 1H-NMR spectroscopy. Enantiomeric excess was determined by SFC.
