Table 3.
Comparison of Wave 1 baseline characteristics of both the overall sample and attrition sample.
| Baseline Characteristic | Wave 3 Data Present | Wave 3 Data Missing | p | |
|---|---|---|---|---|
| (n = 2938) | (n = 1962) | |||
| Mean age in years (SD) | 59.8 (7.9) | 62.88 (9.7) | <0.001 | MWU |
| Female (n (%)) | 1609 (54.8) | 1094 (55.8) | 0.481 | chi |
| Non-frail (n (%)) | 2213 (76.6) | 1258 (66.4) | <0.001 | chi |
| Pre-frail/Frail (n (%)) | 676 (23.4) | 637 (33.6) | <0.001 | chi |
| Mean time to stand (SD) | 7.34 (2.6) | 8.07 (3.4) | <0.001 | MWU |
| Median MMSE (IQR) | 29 (2) | 29 (2) | <0.001 | MWU |
| Multimorbidity (n (%)) | 1239 (42.2) | 997 (50.8) | <0.001 | chi |
| Atrial Fibrillation (n (%)) | 52 (1.8) | 57 (3.0) | 0.008 | chi |
| Parkinson’s disease (n (%)) | 6 (0.2) | 9 (0.5) | 0.114 | chi |
| Diabetes Mellitus (n (%)) | 147 (5.0) | 153 (7.8) | <0.001 | chi |
| Hypertension (n (%)) | 1090 (37.2) | 844 (43.4) | <0.001 | chi |
| Polypharmacy (n (%)) | 396 (13.5) | 434 (22.3) | <0.001 | chi |
| Antihypertensive | chi | |||
| Overall (n (%)) | 803 (27.3) | 750 (38.3) | <0.001 | chi |
| Beta blockers (n (%)) | 274 (9.3) | 289 (14.8) | <0.001 | chi |
| Diuretics (n (%)) | 127 (4.3) | 162 (8.3) | <0.001 | chi |
| ACE inhibitors/Angiotensin receptor blockers (n (%)) | 536 (18.3) | 511 (26.2) | <0.001 | chi |
| Calcium channel blockers (n (%)) | 200 (6.8) | 202 (10.4) | <0.001 | chi |
| Alpha blockers (n (%)) | 28 (1.0) | 43 (2.2) | <0.001 | chi |
| Psychoactive medications | ||||
| Overall (n (%)) | 219 (7.5) | 225 (11.5) | <0.001 | chi |
| Z-drugs (n (%)) | 51 (1.7) | 58 (3.0) | 0.004 | chi |
| Benzodiazepines (n (%)) | 63 (2.2) | 77 (4.0) | <0.001 | chi |
| Antidepressants (n (%)) | 146 (5.0) | 135 (6.9) | 0.005 | chi |
| Orthostatic Intolerance during active stand (n (%)) | 1150 (39.2) | 730 (37.3) | 0.187 | chi |
| At least 1 fall in the past 12 months (n (%)) | 564 (19.2) | 396 (20.2) | 0.395 | chi |
| At least 1 blackout in the past 12 months (n (%)) | 129 (4.4) | 97 (5.0) | 0.369 | chi |
| Lifetime history of syncope (n (%)) | 589 (20.1) | 374 (19.1) | 0.398 | chi |
| Mean baseline SBP (SD) [mmHg] | 134.94 (21.9) | 137.04 (22.8) | <0.001 | MWU |
| Mean baseline HR (SD) [bpm] | 64.52 (9.6) | 65.61 (10.3) | <0.001 | MWU |
Abbreviations: MWU: Mann–Whitney U test (unpaired data); chi: Chi-square test; SD: standard deviation; IQR: interquartile range; bpm: beats per minute.