Ligand optimization^a.

Entry	Ligand	Conv.	Yields
			3a	3b	3d	Overall
1	L7	86%	12%	41%	10%	63%
2	L11	42%	—	9%	—	9%
3	L12	81%	10%	42%	10%	62%
4	L13	23%	1%	13%	—	14%
5	L14	34%	4%	24%	—	28%
6	L15	43%	6%	26%	2%	34%
7	L16	59%	4%	34%	2%	40%
8	L17	83%	6%	46%	6%	58%
9	L18	65%	6%	40%	5%	51%
10	L19	36%	—	17%	—	17%
11	L20	82%	10%	37%	4%	51%
12b	L17	53%	12%	14%	—	26%
13c	L17	58%	10%	43%	4%	54%
14c,d	L17	96%	6%	50%	15%	71%
15c,d,e	L17	—	7%	46%	12%	65%
16 c , d , e , f	L17	—	5%	63%	8%	76%

^aConversions were determined by GC analysis, and yields were determined by ¹H NMR analysis.

^b10 vol% of DMSO was added.

^c50 mol% of Cu₂(OH)₂CO₃ was used instead of Cu(OTf)₂.

^d10 mol% PdCl₂(CH₃CN)₂ was employed.

^e2 equiv. of 1a and 1 equiv. of 2a were used, and the yields were calculated based on the amount of acrylate.

^fReaction was performed at 50 °C for 12 h.