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. 2020 Sep 21;11(41):11244–11258. doi: 10.1039/d0sc02987d

Putative DNA adducts that displayed changes in the DNA of NMC-exposed S. oneidensis. Putative names are reported, as structural identification can only be confirmed by comparison with synthetic standards in future work. [M + H]+ values marked with bold font indicate overlapping [M + H]+ with B. subtilis.

[M + H]+ Fold change Putative name Origin Category
229.0931 12 dIZ Degradation 8-oxo-dG Oxidative stress
244.0928 Only in exposed 5-OH-dC Direct or indirect oxidation via ROS Oxidative stress
260.0877 Only in exposed 5,6-OH-dC Direct or indirect oxidation via ROS Oxidative stress
270.1197 Only in exposed FAPY-A Direct or indirect oxidation via ROS Oxidative stress
284.0989 19 8-oxo-dG Direct or indirect oxidation via ROS Oxidative stress
286.1146 6 FAPY-dG Direct or indirect oxidation via ROS Oxidative stress
300.0939 5 Spiroiminodihydantoin Direct or indirect oxidation via ROS Oxidative stress
310.1146 110 N 6 -hydroxyacetyl-dA Direct or indirect oxidation via ROS Oxidative stress
382.1721 42 N 2 -dimethyldioxane-dG Lipid peroxidation Lipid peroxidation
436.2191 Only in exposed DDE-I-dA Lipid peroxidation Lipid peroxidation
299.1238 66 Acr-dT_I Acrolein Lipid peroxidation
340.1252 165 CE-dG Glycation Glycation
308.0989 337 2-oxo-1,N2-εdG Etheno Alkylation