Putative DNA adducts that displayed changes in the DNA of NMC-exposed S. oneidensis. Putative names are reported, as structural identification can only be confirmed by comparison with synthetic standards in future work. [M + H]+ values marked with bold font indicate overlapping [M + H]+ with B. subtilis.
[M + H]+ | Fold change | Putative name | Origin | Category |
---|---|---|---|---|
229.0931 | 12 | dIZ | Degradation 8-oxo-dG | Oxidative stress |
244.0928 | Only in exposed | 5-OH-dC | Direct or indirect oxidation via ROS | Oxidative stress |
260.0877 | Only in exposed | 5,6-OH-dC | Direct or indirect oxidation via ROS | Oxidative stress |
270.1197 | Only in exposed | FAPY-A | Direct or indirect oxidation via ROS | Oxidative stress |
284.0989 | 19 | 8-oxo-dG | Direct or indirect oxidation via ROS | Oxidative stress |
286.1146 | 6 | FAPY-dG | Direct or indirect oxidation via ROS | Oxidative stress |
300.0939 | 5 | Spiroiminodihydantoin | Direct or indirect oxidation via ROS | Oxidative stress |
310.1146 | 110 | N 6 -hydroxyacetyl-dA | Direct or indirect oxidation via ROS | Oxidative stress |
382.1721 | 42 | N 2 -dimethyldioxane-dG | Lipid peroxidation | Lipid peroxidation |
436.2191 | Only in exposed | DDE-I-dA | Lipid peroxidation | Lipid peroxidation |
299.1238 | 66 | Acr-dT_I | Acrolein | Lipid peroxidation |
340.1252 | 165 | CE-dG | Glycation | Glycation |
308.0989 | 337 | 2-oxo-1,N2-εdG | Etheno | Alkylation |