Fig. 5. Simultaneous activation of nucleotides and peptides in the presence of vesicles made of prebiotic fatty acids. (A) 31P-NMR spectra showing the activation of A3′P in the presence of AcGly, AcAla and ValVal and DA : DOH : DHO (4 : 1 : 1 ratio) vesicles after 12 h in DCI buffer, pH 6. (B) Plot reporting the formation and the hydrolysis of 2′-esters of A3′P under activation conditions in the presence of the dipeptides GlyGly, ValVal or IleIle and DA : DOH : DHO (4 : 1 : 1 ratio) vesicles in DCI buffer, pH 6.
