Fig. 12. Cell-cycle effect by 2a. (A) DEGs associated with cell cycle in response to 2a, (B) representative histogram of the cycle; control (DMSO vehicle) vs.2a, MDA-MB-231 cells were seeded at a density of 2 × 105 cells per well and treated with 2a at 0.1 μM for 24, 48, and 72 h. (C) Bar graph detailing the change in G1, G2/M, and S phase over 24, 48, and 72 h, data are plotted as the mean ± s.e.m (n = 3), (D) bar graph illustrating the % increase in G1 over 72 h after treatment with 2a, data are plotted as the mean ± s.e.m (n = 3) *p < 0.05.
