Fig. 4. Photoregulation of GFP gene silencing with caged Multi-Chol-siGFP self-assembled nanoparticles. (A) Photochemical regulation of GFP gene silencing was observed from fluorescence images. (B) Comparison of the differences in the photomodulation of gene silencing between single cholesterol-modified caged siRNA (Chol-p-siRNA) and the caged Multi-Chol-siGFP self-assembled nanoparticles. The concentration of the native siGFP (AG/SG, PC) is 5 nM. Scale bar = 25 μm. Data are presented as mean ± S.E.M. (n = 3).
