TABLE 2.
Patients Characteristics on ICU Admission During the First and second Waves of Coronavirus Disease 2019 Pandemic
| Variables | First Wave of the COVID-19 Pandemic | Number of Patients | Second Wave of the COVID-19 Pandemic | Number of Patients | p |
|---|---|---|---|---|---|
| Age (yr) | 65 (54–71) | 87 | 67.0 (59.5–74.0) | 128 | 0.078 |
| Body mass index (kg/m2) | 30.8 (26.3–34.6) | 80 | 28.1 (25.1–32.2) | 117 | 0.0056 |
| Chronic kidney disease | 19 (21.8%) | 87 | 25 (19.5%) | 128 | 0.68 |
| Diabetes | 43 (49.4%) | 87 | 59 (46%) | 128 | 0.63 |
| Hypertension | 40 (46%) | 87 | 88 (72.1%) | 122 | 0.0008 |
| Sequential Organ Failure Assessment score | 6 (3–7) | 85 | 4 (3–6) | 120 | 0.021 |
| C-reactive protein (mg/L) | 173 (113–244) | 86 | 111 (63.9–197) | 127 | 0.0005 |
| Bilirubin (mg/dL) | 0.75 (0.54–1.13) | 86 | 0.65 (0.48–0.89) | 126 | 0.036 |
| Creatinine (mg/dL) | 0.97 (0.78–1.36) | 86 | 0.87 (0.70–1.23) | 127 | 0.11 |
| d-dimer (ng/mL) | 1,895 (922–4,717) | 67 | 1,280 (603–2,043) | 118 | 0.0018 |
| Ferritin (µg/L) | 1,968 (746–4,461) | 40 | 1,327 (612–2,725) | 83 | 0.21 |
| Lymphocyte count (103/mm3) | 0.80 (0.56–1.11) | 86 | 0.66 (0.42–0.96) | 127 | 0.010 |
| Platelet count (103/mm3) | 205 (163-268) | 86 | 233 (159–305) | 127 | 0.14 |
| Pao2/Fio2 (mm Hg) | 108 (84.4–134) | 56 | 91.2 (70.5–116) | 80 | 0.028 |
| Mean arterial pressure (mm Hg) | 66.3 (59.7–73.7) | 87 | 71.0 (64.5–77.8) | 128 | 0.027 |
COVID-19 = coronavirus disease 2019.
Quantitative variables are reported as median (Q1–Q3) and categorical variables as number (%). Kruskal-Wallis and Fisher exact tests are used as appropriate.