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. 2021 Jun;128(6):952–955. doi: 10.1016/j.ophtha.2020.10.032

Figure 1.

Figure 1

Multimodal imaging findings: (A–C) family 1, (D, E) family 2, (F–H) family 3, (I–K) family 4, (L–O) family 5, and (P–S) family 6. A–C, Images from family 1 (A) proband, (B) her younger daughter, 4 years of age, and (C) older daughter, 19 years of age. Panels show short-wavelength autofluorescence (SW-AF; leftmost panels: right eye of proband and younger daughter, left eye of older daughter), near infrared reflectance (NIR; middle panels: same eyes as for SW-AF), and OCT (right panels: right eye of proband, left eye of younger daughter, right eye of older daughter). D, E, Images from proband of family 2: (D) pseudocolor image (left eye) showing hyperpigmented lines radiating from fovea and (E) SW-AF (left panel) and NIR (right panel) images from the right macula. Both eyes show peripapillary atrophy. F–H, Images from family 3: (F) left eye of proband (NIR and OCT) and (G, H) right eye of her mother (G, pseudocolor; H, green autofluorescence). I–K, Images from family 4: (I) pseudocolor; (J) SW-AF (left panel), NIR (middle panel), and OCT (right panel) images from the right eye of the proband; (K) SW-AF, NIR, and OCT images from the right macula of the proband’s male affected cousin. Abnormalities appear more evident on NIR compared with SW-AF images. L–O, Images from the proband from family 5: (L) SW-AF images and (M) NIR and OCT images from both eyes of the patient, 31 years of age; (N, O) Corresponding images obtained 3 years later. P–S, Images from the proband from family 6 at 62 years of age: (P) color fundus image of right eye; (Q) color, red-free, and fundus fluorescein images from the left eye; and at 78 years of age: (R) SW-AF image of the left eye and (S) NIR reflectance and OCT images.