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. 2021 Jun;128(6):837–847. doi: 10.1016/j.ophtha.2021.02.007

Table 3.

Hazard Ratio of Incident Cataract Surgery Across Different Alcohol Beverages among Drinkers Compared with Nondrinkers in EPIC-Norfolk


Amount of Alcohol Intake (g)
No. of Incident Cases No. at Risk Univariable Model
Multivariable Model
Hazard Ratio (95% CI) P Value Hazard Ratio (95% CI) P Value
Nondrinkers 1118 4516 Ref Ref
Wine drinkers
 First tertile 1626 7902 0.76 (0.70–0.82) <0.001 0.98 (0.91–1.06) 0.57
 Second tertile 688 4169 0.58 (0.53–0.64) <0.001 0.81 (0.74–0.89) <0.001
 Third tertile 547 3721 0.52 (0.47–0.58) <0.001 0.77 (0.69–0.85) <0.001
P for trend <0.001 <0.001
Nondrinkers 1118 4516 Ref Ref
Beer drinkers
 First tertile 985 5532 0.65 (0.59–0.71) <0.001 0.92 (0.84–1.01) 0.07
 Second tertile 392 2524 0.56 (0.50–0.63) <0.001 0.87 (0.77–0.99) 0.033
 Third tertile 360 2567 0.52 (0.46–0.59) <0.001 0.91 (0.80–1.04) 0.18
P for trend <0.001 0.07
Nondrinkers 1118 4516 Ref Ref
Spirits drinkers
 First tertile 642 3591 0.64 (0.58–0.71) <0.001 0.94 (0.85–1.04) 0.23
 Second tertile 815 4524 0.66 (0.61–0.72) <0.001 0.91 (0.83–1.00) 0.06
 Third tertile 356 1842 0.76 (0.68–0.86) <0.001 0.86 (0.76–0.97) 0.016
P for trend <0.001 0.009

BMI = body mass index; CI = confidence interval; EPIC = European Prospective Investigation of Cancer.

Multivariable model adjusted for age, sex, ethnicity, Townsend deprivation index, BMI, smoking, and diabetes status.

Bold values denote statistical significance at the P < 0.05 level.