Table 1.
Univariate analyses comparing characteristics (demographics, pre-existing comorbidities and early symptoms at presentation) in 282 community-dwelling COVID-19 patients over 50 years according to occurrence or not of a critical outcome (ICU-admission or death) across clinical course.
| Variable | Outcome |
|||
|---|---|---|---|---|
| Non-ICU/death (N = 218) n (%) |
ICU/death (N = 64) n (%) |
p-value | Total (N = 282) n (%) |
|
| Demographics | ||||
| Age: 50–64 yrs | 142 (65.1) | 13 (20.3) | <0.001 | 155 (54.9) |
| 65–79 yrs | 56 (25.7) | 31 (48.4) | 87 (30.9) | |
| ≥80 yrs | 20 (9.2) | 20 (31.3) | 40 (14.2) | |
| Sex: Men Women |
101 (46.3) 117 (53.7) |
39 (60.9) 25 (39.1) |
0.040 | 140 (49.6) 142 (50.4) |
| Comorbidities | ||||
| Neurological | 4 (1.8) | 4 (6.3) | 0.061 | 8 (2.8) |
| Renal | 18 (8.3) | 11 (17.2) | 0.039 | 29 (10.3) |
| Cancer | 24 (11.0) | 10 (15.6) | 0.319 | 34 (12.1) |
| Rheumatic | 4 (1.8) | 1 (1.6) | 0.885 | 5 (1.8) |
| Respiratory | 28 (12.8) | 21 (32.8) | <0.001 | 49 (17.4) |
| Cardiac | 43 (19.7) | 23 (35.9) | 0.007 | 66 (23.4) |
| Atrial fibrillation | 16 (7.3) | 9 (14.1) | 0.096 | 25 (8.9) |
| Liver disease | 3 (1.4) | 3 (4.7) | 0.107 | 6 (2.1) |
| Hypertension | 83 (38.1) | 37 (57.8) | 0.005 | 120 (42.6) |
| Diabetes | 31 (14.2) | 23 (35.9) | <0.001 | 54 (19.1) |
| Smoking | 21 (9.6) | 4 (6.3) | 0.402 | 25 (8.9) |
| Alcoholism | 5 (2.3) | 2 (3.1) | 0.707 | 7 (2.5) |
| Obesity | 54 (24.8) | 18 (28.1) | 0.588 | 72 (25.5) |
| Symptoms | ||||
| Cough | 153 (70.2) | 38 (59.4) | 0.104 | 191 (67.7) |
| Sore throat | 31 (14.2) | 6 (9.4) | 0.313 | 37 (13.1) |
| Rinorrhea (RN) | 26 (11.9) | 2 (3.1) | 0.038 | 28 (9.9) |
| Myalgias | 73 (33.5) | 4 (6.3) | <0.001 | 77 (27.3) |
| Fatigue | 67 (30.7) | 18 (28.1) | 0.689 | 85 (30.1) |
| Headache | 53 (24.3) | 6 (9.4) | 0.010 | 59 (20.9) |
| Ageusia/disgeusia (AG) | 28 (12.8) | 3 (4.7) | 0.067 | 31 (11.0) |
| Anosmia (AN) | 34 (15.6) | 3 (4.7) | 0.023 | 37 (13.1) |
| Cluster RN/AG/AN | 61 (28.0) | 4 (6.3) | <0.001 | 65 (23.0) |
| Chest pain | 31 (14.2) | 6 (9.4) | 0.313 | 37 (13.1) |
| Dyspnoea | 65 (29.8) | 47 (73.4) | <0.001 | 112 (39.7) |
| Vomiting | 12 (5.5) | 3 (4.7) | 0.798 | 15 (5.3) |
| Diarrhoea | 53 (24.3) | 15 (23.4) | 0.886 | 68 (24.1) |
| Confusion | 5 (2.3) | 10 (15.6) | <0.001 | 15 (5.3) |
| General discomfort | 93 (42.7) | 26 (40.6) | 0.772 | 119 (42.2) |
| Fever | 154 (70.6) | 46 (71.9) | 0.849 | 200 (70.9) |
NOTE: Early symptoms were considered within the first five days of the onset of disease. p-values were calculated by using chi-squared or Fisher's test as appropriate.