Skip to main content
. 2020 Oct 1;11(42):11548–11553. doi: 10.1039/d0sc03883k

Scope of the mono and disubstitution reactiona.

graphic file with name d0sc03883k-u2.jpg
a

Condition A: reactions were performed with 0.6 mmol of 1, 0.2 mmol of TMSBr, and 9.0 mol% of Al(C6F5)3(tol)0.5 in 1.5 mL of DCE at 60 °C for 48 h; condition B: reactions were performed with 0.2 mmol of 1, 0.8 mmol of TMSBr, and 4.5 mol% of Al(C6F5)3(tol)0.5 in 1.5 mL of DCE at 120 °C for 24 h; isolated yields are reported.

b

The reaction was performed at 80 °C.

c

TMSI was used instead of TMSBr.

d

The reaction was carried out with 13.5 mol% of Al(C6F5)3(tol)0.5.

e

4 equiv. of 1 was used.

f

The reaction was performed with 5 equiv. of TMSBr.