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Circulating cell-free DNA concentrations and DNA integrity.
| Parameter (ng/mL) | Breast Cancer Patients | 95% CI of Mean | p-Value | |
|---|---|---|---|---|
| TI | T2 | |||
| ALU 115 | 2.24 ± 0.80 | 1.67 ± 0.66 | −0.94–(−0.21) | 0.003 * |
| ALU 247 | 2.73 ± 0.11 | 2.12 ± 0.69 | −086–(−0.36) | <0.0001 * |
| cfDNA integrity | 1.22 ± 0.14 | 1.27 ± 1.04 | −0.32–0.42 | 0.788 |
T1: before commencement of chemotherapy: T2: after the 3rd cycle of chemotherapy. * p-value ≤ 0.05 is statistically significant. CI = confidence interval.
