Table 3.
Geometric means (95% confidence limits) for EB–GII (fmol/ml) stratified by GSTT1 CNV and race/ethnicity among smokers
| GSTT1 gene deletion genotypea | N | Geometric mean (95% CI) | P-value |
|---|---|---|---|
| Allb | 323 | ||
| 1/1 | 70 | 0.92 (0.68–1.22) | 0.2689 |
| 1/0 | 157 | 0.80 (0.65–0.96) | |
| 0/0 | 96 | 1.02 (0.79–1.30) | |
| Whitesc | 109 | ||
| 1/1 | 32 | 0.81 (0.52–1.22) | 0.2385 |
| 1/0 | 46 | 0.67 (0.45–0.97) | |
| 0/0 | 31 | 1.09 (0.68–1.70) | |
| Native Hawaiiansc | 109 | ||
| 1/1 | 27 | 0.96 (0.59–1.54) | 0.1537 |
| 1/0 | 59 | 0.66 (0.47–0.88) | |
| 0/0 | 23 | 1.06 (0.63–1.77) | |
| Japanese Americansc | 105 | ||
| 1/1 | 11 | 1.28 (0.55–2.90) | 0.9537 |
| 1/0 | 52 | 1.42 (0.93–2.15) | |
| 0/0 | 42 | 1.33 (0.84–2.07) |
aThe GSTT1 genotypes are coded as follows: 1/1 = 2 copies of gene; 1/0 = 1 copy of the gene; 0/0 = gene deletion.
bThe overall analyses have been adjusted for sex, age, BMI, NE, batch and race.
cThe race/ethnic specific analyses have been adjusted for sex, age, BMI, NE and batch.