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. 2020 Jul 17;11(31):8249–8255. doi: 10.1039/d0sc01928c

Minimum inhibitory concentrations (MICs) of pladienolide B (1) and its congeners (2–6) against NS-1 mouse myeloma ATCC TIB-18 and NFF human neonatal foreskin fibroblast cells ATCC PCS-201.

Compound MIC (μg mL−1)
NS-1 NFF
1 0.001 0.013
2 0.001 0.04
3 0.05 0.6
4 0.1 0.4
5 0.63 10
6 0.08 1.25