Fig. 9. (a) SDS-PAGE analysis shows the light dependence of the cleavage of BSA by l-QDs with exposure to different kinds of light for 12 h. Lane 1, molecular marker; lane 2, BSA; lane 3, BSA + RCP; lane 4, BSA + LP; lane 5, BSA + LCP. (b) PL spectra of BSA in the absence and presence of different concentrations of l-QDs. (c) CD spectra of BSA photocleavage at different reaction times. (d) TEM image of l-QDs after the cutting of BSA. (e) SDS-PAGE analysis shows the results for the cleavage of BSA by l-QDs under LCP irradiation for 6 h: lane 1, molecular marker; lane 2, BSA control; lane 3, BSA + QD; lane 4, BSA + QD + KI; lane 5, BSA + QD + ethanol; lane 6, BSA + QD + NaN₃. (f) The recyclability of l-QDs for BSA cutting.⁹⁷ Adapted with permission from ref. 97. Copyright 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. (g) Synthesis of penicillamine-modified Fe_xCu_ySe nanoparticles and illustration of the inhibition and disassembly effects of d-Pen Fe_xCu_ySe on Aβ42 aggregation and mitigation of potential neurotoxicity in an AD mice model. (h–i) CD spectra of Aβ fibrils with l/d-NPs and NIR at 190–250 nm (h) and 400–1000 nm (i).⁹⁸ Adapted with permission from ref. 98. Copyright 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.