Table 4.

Associations between systemic rheumatic disease or matched comparator status and COVID-19 hospital admission outcomes

		Patients with a systemic rheumatic disease (n=57)	Comparators (n=232)
Outcomes at initial admission to hospital
Intensive care unit admission		29 (51%)	79 (34%)
	Unadjusted OR (95% CI)	2·00 (1·09–3·67)	1 (ref)
	Adjusted model OR (95% CI)	2·08 (1·09–3·96)	1 (ref)
Mechanical ventilation		22 (39%)	45 (19%)
	Unadjusted OR (95% CI)	2·59 (1·35–4·94)	1 (ref)
	Adjusted model OR (95% CI)	2·60 (1·32–5·12)	1 (ref)
In-hospital mortality		12 (21%)	38 (16%)
	Unadjusted OR (95% CI)	1·48 (0·69–3·17)	1 (ref)
	Adjusted model OR (95% CI)	1·78 (0·79–4·02)	1 (ref)
Outcomes after discharge*
Discharged to rehabilitation or nursing facility		16 (36%)	80 (41%)
	Unadjusted OR (95% CI)	0·79 (0·40–1·54)	1 (ref)
	Adjusted model OR (95% CI)	0·90 (0·43–1·88)	1 (ref)
Readmission to hospital within 60 days		5 (11%)	22 (11%)
	Unadjusted OR (95% CI)	0·98 (0·35–2·74)	1 (ref)
	Adjusted model OR (95% CI)	1·08 (0·37–3·16)	1 (ref)
Mortality during and after hospital stay
In-hospital mortality or within 60 days after discharge		13 (23%)	50 (22%)
	Unadjusted OR (95% CI)	1·08 (0·54–2·15)	1 (ref)
	Adjusted model OR (95% CI)	1·20 (0·58–2·47)	1 (ref)
In-hospital mortality or at any point after discharge		17 (30%)	57 (25%)
	Unadjusted OR (95% CI)	1·30 (0·69–2·48)	1 (ref)
	Adjusted model OR (95% CI)	1·48 (0·75–2·91)	1 (ref)

Data are n (%) or OR (95% CI). Matching factors were age, sex, and date of initial positive PCR for SARS-CoV-2. Model adjusted for race, smoking status, and days between initial PCR positivity for SARS-CoV-2 and COVID-19 hospital admission. OR=odds ratio.

^*n=45 for patients with a systemic rheumatic disease; n=194 for comparators.