| Ru |
NKP1339 (Ru9) |
ICD |
Calreticulin cell surface expression (flow cytometry), HMGB1 release to extracellular space (ELISA) |
195
|
| Pt |
Oxaliplatin (Pt3) |
ICD |
HMGB1 release to extracellular space (ELISA) |
196
|
| Calreticulin surface expression (flow cytometry), HMGB1 motility (western blot) |
197
|
| Fe |
Dinitrosyl Fe complex (Fe3†) |
Apoptosis |
Annexin-V/PI apoptosis assay (FACS) |
198
|
| PARP, caspases 3 and 9 (immunohistochemistry) from in vivo tumour tissue |
| Cu |
Cu-TSC (Cu2†) |
Apoptosis |
Annexin V-FITC/PI apoptosis detection, caspase-3 assay, caspases 8 and 9 (qPCR) |
199
|
| Ru |
RAPTA-C (Ru12) |
Apoptosis |
Cytochrome c release, procaspase-9 (western blot) |
200
|
| Annexin-V/PI apoptosis assay (FACS) |
| Pd |
[Pd(bipy)(O,O′-dkt)]+ (Pd2†) |
Apoptosis |
Annexin-V/PI apoptosis assay (FACS), mitochondrial membrane potential using JC-1 dye (FACS) |
201
|
| Os |
FY26 (Os4) |
Apoptosis |
FlowCellect Cytochrome c Kit (FACS) |
202
|
| MitoCapture Apoptosis Detection Kit (confocal) |
| Ir |
Ir-TEMPO1 (Ir10†) |
Apoptosis |
Mitochondrial membrane potential using JC-10 dye (FACS) |
203
|
| Pt |
Cisplatin (Pt1) |
Apoptosis |
Annexin-V/PI staining (FACS), mitochondrial membrane potential (JC-1), caspase-3 |
204
|
| Pt |
Carboplatin (Pt2) |
Apoptosis |
Cytochrome c release, PARP cleavage/caspases (western blot) |
205
|
| Au |
[Au(L2b)PPh3] (Au3†) |
Apoptosis |
Mitochondrial membrane potential and caspase-3 activity (FACS) |
206
|
| Mn |
Adpa-Mn (Mn1†) |
Apoptosis and ACD |
PARP-cleavage/LC-3/ATG7 expression (western blot) |
207
|
| Annexin-V/PI apoptosis assay (FACS) |
| As |
As2O3 (As3† in aqueous solution) |
ACD |
MEK/ERK pathways (autophagy inhibitor studies, western blot) |
208
|
| Pt |
Mono-Pt (Pt16†) |
ACD |
Anti-LC3 antibody (immunohistochemistry) |
209
|
| Ru |
[(p-Cym)Ru(TsEn)Cl] (Ru11†) |
Necrosis |
Annexin-V/PI assay (FACS) |
103
|
| Ru |
Cyclometallated Ru |
Necroptosis |
p-RIPK1/p-RIPK3 expression (western blot) |
210
|
