Table 5.

Pup preweaning physical and neurofunctional development. For pinna unfolding (pre-cull), the total number of litters/pups evaluated were 22/285 and 21/273 for the control and BNT162b2 groups, respectively. For eye opening (post-cull), the total number evaluated were 22/176 and 21/163 for the control and BNT162b2 groups, respectively. For both reflex endpoint (post-cull), the total number evaluated were 22/175 and 21/163 for the control and BNT162b2 groups, respectively.

	Control (saline)	BNT162b2
Pinna unfolding (day at which 100 % pups attained landmark)	4	4
Eye opening (day at which 100 % pups attained landmark)	16	16
Auditory reflex (% pups positive)	100	100
Pupillary reflex (% pups positive)	100	100