Fig. 6. (A) The qRT-PCR and (B) western blot analyses of the expression levels of the Egr-1 mRNA and Egr-1 protein, respectively, in the untreated MCF-7 cells (a) and MCF-7 cells treated with non-Apt/Dz ((b) 3 μM), Apt/Dz* ((c) 3 μM) and Apt/Dz ((d) 3 μM). (C) MTT cell proliferation assays for the MCF-7 (with/without the pretreatment with the tamoxifen drug) and MCF-10A cells after 48 h incubation with various concentrations of Apt/Dz catenane and Dz. Error bars: SD, n = 3. *p < 0.05, **p < 0.01.
