. 2021 May 27;7(5):e29298. doi: 10.2196/29298

Table 1.

Mean and percent change in EMS runs involving opioid overdoses, naloxone administrations, and multiple naloxone administrations in Guilford County, North Carolina before and after the COVID-19 state of emergency declaration.

Outcomes	COVID-19 period^a, mean (SD)^b	Comparison period
		Previous 29 weeks^c				Same 29 weeks of previous year^d
		Mean (SD)^b	COVID-19 period change (%)^e,f	P value	Mean (SD)^b		COVID-19 period change (%)^e	P value
Opioid overdose–related EMS^g runs	25.6 (5.6)	18.6 (6.6)	37.4	<.001	20.6 (6.5)		24.3	.003
Naloxone administrations	22.3 (6.2)	14.1 (6.0)	57.8	<.001	17.2 (6.9)		29.7	.006
Multiple naloxone administrations	5.0 (1.9)	2.7 (1.9)	84.8	<.001	3.3 (1.8)		51.5	<.001

^aMarch 10 to September 30, 2020.

^bWeekly mean and SD of outcome during period.

^cSeptember 2, 2019, to March 9, 2020.

^dMarch 13 to October 5, 2019.

^e(COVID-19 period mean – comparison period mean) / comparison period mean.

^fThe percentage changes shown may not correspond exactly to the values shown due to rounding.

^gEMS: emergency medical services.