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. 2021 Feb 3;320(5):R641–R652. doi: 10.1152/ajpregu.00310.2020

Table 6.

Blood parameters

Pre-Drink Consumption
Post-Drink Consumption (Δ from Pre)
Water Diet Sucrose HFCS P Value Water Diet Sucrose HFCS P Value
Sodium, mmol/L 139 ± 1 139 ± 1 138 ± 1 139 ± 2 0.21 0 ± 1 0 ± 1 0 ± 1 0 ± 2 0.94
Potassium, mmol/L 4.2 ± 0.3 4.4 ± 0.4 4.3 ± 0.3 4.2 ± 0.2 0.17 0.0 ± 0.2 0.0 ± 0.3 −0.2 ± 0.2 −0.1 ± 0.2 0.12
Chloride, mmol/L 105 ± 1 104 ± 2 103 ± 2 105 ± 2 0.017 0 ± 1 −1 ± 1 0 ± 2 −1 ± 2 0.16
Glucose, mg/dL 88 ± 6 88 ± 5 85 ± 7 88 ± 6 0.35 −4 ± 9 1 ± 5 42 ± 21W,D 36 ± 28W,D <0.001
Fructose, µmol/L 127 ± 37 133 ± 40 128 ± 37 127 ± 43 0.057 2 ± 12 8 ± 12 189 ± 81W,D 286 ± 99W,D,S <0.001
Osmolality, mosmol/kg 284 ± 2 285 ± 2 284 ± 2 285 ± 3 0.67 −1 ± 2 0 ± 1 2 ± 2W,D 2 ± 2D 0.005
Copeptin, pmol/L 9.5 ± 2.8 7.6 ± 1.9W 8.5 ± 2.3 9.6 ± 2.7D 0.016 0.3 ± 0.9 0.1 ± 1.2 0.1 ± 1.2 0.8 ± 1.0 0.36
Uric acid, mg/dL 6.0 ± 1.0 6.0 ± 1.1 5.9 ± 1.2 6.3 ± 1.2 0.29 −0.1 ± 0.1 −0.1 ± 0.8 0.2 ± 0.2 0.3 ± 0.4W,D 0.006

Data are presented as absolute values for pre-drink consumption and change values from pre-to-post drink consumption as means ± SD; n = 12 (10 M, 2 F). Comparisons at pre-drink consumption were made using a one-way ANOVA. At post-drink consumption, comparisons were made using a mixed-effects model where significant fixed effects (drink) were analyzed using post hoc Sidak’s test. WDifferent from Water (P ≤ 0.05); Ddifferent from Diet (P ≤ 0.05); Sdifferent from Sucrose (P = 0.04). P value columns are main effect of drink. All data except chloride were previously published by Chapman et al. (12). HFCS, high-fructose corn syrup.